发明名称 |
Method and apparatus to compensate for gas chromatograph column permeability |
摘要 |
In a gas chromatograph system having a column with a stationary phase and a carrier gas moving through the column to contact the stationary phase, the system being useful for detecting analytes in a sample, a method and apparatus for predicting the retention times for the analytes under various conditions, the method utilizing the steps of: a) detecting the analytes under a number of sets of given conditions; b) calculating values for various parameters characteristic of the system based on a mathematical model that includes a correction to compensate for the permeability of said column to said carrier gas; c) entering into the model the values for the characteristic parameters and at least one further set of conditions; and d) using the model to predict retention times for conditions other than those of step a; the apparatus composed of a data handling system including a model for predicting retention times at a variety of conditions of operation of the system, the model having a first set of inputs including retention times determined during a number of operating condition sets; and a second input representative of the permeability of the column to the carrier gas, the data handling system possessing a prediction mechanism for putting into the model a set of conditions other than those of a) above and for putting in the set of parameters, and for predicting retention times for those conditions other than those of a).
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申请公布号 |
US5915269(A) |
申请公布日期 |
1999.06.22 |
申请号 |
US19980059927 |
申请日期 |
1998.04.14 |
申请人 |
THE PERKIN-ELMER CORPORATION |
发明人 |
CAHILL, JERRY E.;TRACY, DAVID H. |
分类号 |
G01N30/02;G01N30/60;G01N30/86;G01N30/88;(IPC1-7):B01D15/08;G06F15/20 |
主分类号 |
G01N30/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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