ENANTIOMERICALLY PURE .BETA.-D-DIOXOLANE NUCLEOSIDES WITH SELECTIVE ANT I-HEPATITIS .BETA. VIRUS ACTIVITY

摘要

The invention is a method for the treatment of humans infected with HBV that includes administering an HBV treatment amount of an enatiomerically pure .beta.-D-dioxolanyl purine nucleoside of formula (I), wherein R is OH, Cl, NH2 or H, and X is selected from the group consisting of alkyl, acyl, monophosphate, diphosphate, and triphosphate, or its pharmaceutically acceptable salt.