发明名称 |
COMPUESTOS HETEROCICLICOS, COMPOSICIONES FARMACEUTICAS QUE LOS COMPRENDEN Y METODOS PARA INHIBIR LA LIBERACION DEL PEPTIDO � - AMILOIDE Y/O SU SINTESIS MEDIANTE EL USO DE DICHOS COMPUESTOS |
摘要 |
Disclosed are compounds which inhibit beta -amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta -amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
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申请公布号 |
PE59399(A1) |
申请公布日期 |
1999.06.21 |
申请号 |
PE19980000144 |
申请日期 |
1998.02.27 |
申请人 |
ATHENA NEUROSCIENCES, INC.;ELI LILLY AND COMPANY |
发明人 |
AUDIA, JAMES E.;LATIMER, LEE H.;PORTER, WARREN J.;DROSTE, JAMES;THORSETT, EUGENE D.;NISSEN, JEFFREY S. |
分类号 |
C07D233/02;C07D243/12;A61K31/41;A61K31/4164;A61K31/421;A61K31/4245;A61K31/425;A61K31/426;A61K31/55;A61K31/551;A61K31/5513;A61P25/28;C07D223/18;C07D233/28;C07D243/14;C07D243/24;C07D257/04;C07D263/16;C07D271/06;C07D277/10;C07D277/12;C07D409/12 |
主分类号 |
C07D233/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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