发明名称 Cyclic peptide derivatives
摘要 Compounds of the formula Iin whichX is Gly, Ala or NH-NH-CO,R1 is a radical of the formula II and R2,R3 and R4 have the meanings indicated in claim 1,and their salts,can be used as integrin inhibitors, in particular for the prophylaxis and treatment of disorders of the circulation, in thrombosis, cardiac infarct, coronary heart disorders, arteriosclerosis, in pathological processes which are supported or propagated by angiogenesis and in tumour therapy.
申请公布号 ZA9711392(B) 申请公布日期 1999.06.18
申请号 ZA19970011392 申请日期 1997.12.18
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 发明人 GUENTER HOELZEMANN;SIMON GOODMAN;CLAUS FITTSCHEN
分类号 C07K7/64;A61K38/00;A61K38/12;A61P7/02;C07K7/56 主分类号 C07K7/64
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