Transgenes nicht-menschliches Säugetier mit einer onkogenen Mutante des Raf-1-Gens

摘要

The invention relates to a transgenic non-human mammal whose cells express a constitutively active oncogenic mutant of the kinese-domain of the Raf-1-gene or a protein coded by a corresponding normal allele or derivative of the A, B or c-Raf-1 gene.