Novel salts of the antidiabetic agent metformin are provided which are metformin salts of dibasic acids (2:1 molar ratio), preferably metformin (2:1) fumarate and metformin (2:1) succinate, which may be employed alone or in combination with another antihyperglycemic agent such as glyburide, for treating diabetes. A method for treating diabetes employing the novel metformin salt by itself or in combination with another antidiabetic agent is also provided.
申请公布号
WO9929314(A1)
申请公布日期
1999.06.17
申请号
WO1998US25104
申请日期
1998.12.01
申请人
BRISTOL-MYERS SQUIBB COMPANY
发明人
TIMMINS, PETER;WINTER, WILLIAM, J.;SRIVASTAVA, SUSHIL, K.;BRETNALL, ALISON;WEI, CHENKOU;POWERS, GERALD, L.