| 发明名称 |
NEW COMPOUNDS |
| 摘要 |
There are provided compounds of formula (I), wherein R<1>, R<2>, R<3>, Rx, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
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| 申请公布号 |
WO9929664(A1) |
申请公布日期 |
1999.06.17 |
| 申请号 |
WO1998SE02187 |
申请日期 |
1998.12.01 |
| 申请人 |
ASTRA AKTIEBOLAG;KARLSSON, OLLE;LINSCHOTEN, MARCEL;NYSTROEM, JAN-ERIK |
发明人 |
KARLSSON, OLLE;LINSCHOTEN, MARCEL;NYSTROEM, JAN-ERIK |
| 分类号 |
A61K38/00;A61P7/02;A61P43/00;C07D207/16;C07K5/06;(IPC1-7):C07D207/16;A61K38/05 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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