摘要 |
<p>A method for efficiently separating aspartame (APM) from APM derivative N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine methyl ester and thus purifying APM and the above-mentioned APM derivative each at a high purity, which comprises subjecting, for example, an aqueous solution containing APM and APM derivative to column chromatography with the use of a nonpolar highly porous polymer resin.</p> |