发明名称 |
PEPTIDE ANTAGONISTS OF VASCULAR ENDOTHELIAL GROWTH FACTOR |
摘要 |
The present invention provides isolated polypeptides having VEGF antagonist activity, pharmaceutical compositions and methods of treatment. The polypeptides of the invention include polypeptides comprising a portion of SEQ ID NO:1 having VEGF antagonist activity, polypeptides comprising SEQ ID NO:2 or a portion thereof having VEGF antagonist activity, and a polypeptide having the structure of formula (I), set forth above. The present invention further includes analogs and derivatives of these polypeptides having VEGF antagonist activity.
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申请公布号 |
WO9929861(A1) |
申请公布日期 |
1999.06.17 |
申请号 |
WO1998US26103 |
申请日期 |
1998.12.09 |
申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION;KLAGSBRUN, MICHAEL;SOKER, SHAY |
发明人 |
KLAGSBRUN, MICHAEL;SOKER, SHAY |
分类号 |
C12N15/09;A61K31/711;A61K38/00;A61K48/00;A61P9/00;A61P19/02;A61P29/00;A61P35/00;A61P35/04;A61P43/00;C07K14/52;C07K14/71;C12N15/19;(IPC1-7):C12N15/19;A61K38/19 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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