发明名称 ADAMANTANE DERIVATIVES
摘要 The invention provides adamantane derivatives represented by formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In said formula (I), A represents a group CH2 or an oxygen atom; B represents a hydrogen or halogen atom; D represents a group CH2, OCH2, NHCH2 or CH2CH2; R represents a phenyl, benzothiazolyl, indolyl, indazolyl, purinyl, pyridyl, pyrimidinyl or thiophenyl group, each of which may be optionally substituted by one or more substituents.
申请公布号 CA2312889(A1) 申请公布日期 1999.06.17
申请号 CA19982312889 申请日期 1998.12.01
申请人 ASTRAZENECA UK LIMITED 发明人 MORTIMORE, MICHAEL;BROUGH, STEPHEN;BAXTER, ANDREW;MCINALLY, THOMAS;CLADINGBOEL, DAVID
分类号 C07D295/08;A61K31/16;A61K31/167;A61K31/381;A61K31/40;A61K31/403;A61K31/404;A61K31/4045;A61K31/416;A61K31/4164;A61K31/428;A61K31/44;A61K31/445;A61K31/4453;A61K31/52;A61K31/5375;A61P19/00;A61P19/02;A61P29/00;A61P37/06;C07C233/08;C07C233/15;C07C233/25;C07C233/26;C07C235/16;C07C237/04;C07C237/08;C07D209/04;C07D209/08;C07D209/14;C07D209/16;C07D213/40;C07D213/75;C07D221/22;C07D231/54;C07D231/56;C07D233/60;C07D239/42;C07D277/62;C07D277/64;C07D295/092;C07D295/12;C07D295/135;C07D333/40;C07D473/34;C07D493/08;C07D521/00;(IPC1-7):C07C233/25;A61K31/415;A61K31/425 主分类号 C07D295/08
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