| 发明名称 |
HETEROCYCLIC ESTERS AND AMIDES |
| 摘要 |
<p>This invention relates to neurotrophic low molecular weight, small molecule heterocyclic esters and amides having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.</p> |
| 申请公布号 |
CZ9900660(A3) |
申请公布日期 |
1999.06.16 |
| 申请号 |
CZ19990000660 |
申请日期 |
1997.08.20 |
| 申请人 |
GUILFORD PHARMACEUTICALS INC. |
发明人 |
LI JIA-HE;HAMILTON GREGORY S. |
| 分类号 |
C07D261/02;A61K31/41;A61K31/4164;A61K31/426;A61K31/454;A61K31/535;A61K31/54;A61P25/00;A61P25/16;A61P25/28;C07D233/02;C07D241/04;C07D263/02;C07D265/28;C07D265/30;C07D267/02;C07D277/06;C07D279/12;C07D417/12;(IPC1-7):C07D267/02;C07D277/04;A61K31/495;A61K31/53;A61K31/55 |
主分类号 |
C07D261/02 |
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