发明名称 Inhibitors of farnesyl-protein transferase
摘要 The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
申请公布号 AU1611199(A) 申请公布日期 1999.06.16
申请号 AU19990016111 申请日期 1998.11.30
申请人 MERCK & CO., INC. 发明人 TERRENCE M. CICCARONE;S. JANE DESOLMS
分类号 C07D471/04 主分类号 C07D471/04
代理机构 代理人
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