发明名称 Substituted pyrrole derivatives as cell adhesion inhibitors
摘要 Substituted pyrrole derivatives of Formula (I) are antagonists of VLA-4 and/or alpha 4 beta 7, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical compositions and are suitable for use in the treatment of asthma, allergies, inflammation, multiple sclerosis, and other inflammatory and autoimmune disorders.
申请公布号 AU1463499(A) 申请公布日期 1999.06.15
申请号 AU19990014634 申请日期 1998.11.18
申请人 MERCK & CO., INC. 发明人 LINDA CHANG;WILLIAM K. HAGMANN;MALCOLM MACCOSS
分类号 A61K38/00;C07D207/48;C07D403/12;C07F9/572;C07K5/06;C07K5/078 主分类号 A61K38/00
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