发明名称 BENZOFURAN CARBOXAMIDES AND THEIR THERAPEUTIC USE
摘要 Compounds having the formula (i), wherein the groups R1, R2, R3, R4 and R5 are defined herein. The compounds of the present i nvention can be utilised to treat disease states capable of being modulated by inhibition of proteins which mediate cellular activ ity, such as tumour necrosis factor (TNF) and/or phosphodiesteras e IV (PDE IV).
申请公布号 SK160498(A3) 申请公布日期 1999.06.11
申请号 SK19980001604 申请日期 1997.05.20
申请人 DARWIN DISCOVERY LIMITED 发明人 DYKE HAZEL J.;MONTANA JOHN G.;LOWE CHRISTOPHER;KENDALL HANNAH J.;SABIN VERITY M.
分类号 C07D307/79;A61K31/00;A61K31/34;A61K31/343;A61K31/345;A61K31/415;A61K31/4155;A61K31/425;A61K31/435;A61K31/4353;A61K31/4375;A61K31/44;A61K31/4427;A61K31/443;A61K31/445;A61K31/505;A61K31/506;A61K31/53;A61K31/535;A61K31/5375;A61K31/5377;A61P9/10;A61P11/00;A61P11/06;A61P11/14;A61P11/16;A61P17/06;A61P19/10;A61P25/18;A61P25/28;A61P29/00;A61P31/10;A61P35/02;A61P37/00;A61P37/08;A61P43/00;C07D;C07D307/80;C07D307/81;C07D307/82;C07D307/84;C07D307/86;C07D403/12;C07D403/14;C07D405/04;C07D405/12;C07D405/14;C07D407/14;C07D417/04;C07D417/12;C07D417/14;C07D471/04 主分类号 C07D307/79
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