Bio-absorbable segmented copolymer(s) for medical appliances
摘要
Bioabsorbable, biocompatible segmented copolymers having a Young's modulus of less than 1.379 GPa (200,000 psi) and comprising: (a) 30-95 mol% of a prepolymer consisting of 5-95 mol% iota -caprolactone units and 5-95 mol% p-dioxanone units; and (b) 5-70 mol% of glycolide units. Independent claims are also included for the following: (1) Preparation process for a segmented polymer involving: (i) polymerisation of p-dioxanone and iota -caprolactone in the presence of a catalyst and an initiator to form a prepolymer; and (ii) copolymerising the prepolymer with 5-70 mol% glycolide. (2) A segmented polymer obtained comprising 10-45 mol% glycolide units and 55-90 mol% p-dioxanone and iota -caprolactone units.