| 摘要 |
PROBLEM TO BE SOLVED: To obtain the subject inhibitor comprising an extract of Sambucus nigra L., as an active ingredient, useful as a therapeutic agent for acute arteritis, pulmonary emphysema, arteriosclerosis, arthrorheumatism, metastasis of cancer, infiltration, etc., capable of preventing aging of skin by recovering and maintaining tension and elasticity of skin. SOLUTION: This neutrophil esterase inhibitor comprises an extract of Sambucus nigra L., as an active ingredient. One or a mixed solvent of two or more selected from among methanol, ethanol, 1,3-butylene glycol and purified water is preferable as the extracting solvent in obtaining the extract of Sambucus nigra L. A method for immersing Sambucus nigra L., in the solvent at room temperature in a cooled or heated state, etc., may be cited as the extraction method. The extraction is preferably carried out by using the solvent in an amount of 0.5-100 times as much as Sambucus nigra L., under normal pressure at room temperature to the boiling point of the solvent for 2 hours to 2 weeks. A dose of the plant extract is preferably 5-500 mg/day calculated as a dried weight. |
