摘要 |
PROBLEM TO BE SOLVED: To obtain a collagenase inhibitor capable of specifically inhibiting interstitial collagenase produced by a mesechymal cell such as fibroblast, etc., an eosinophils, etc., effective for improving and preventing morbid states related to collagenase, such as inflammation, wound, metastasis of cancer, ulceration, aging of skin, etc. SOLUTION: This inhibitor contains one or more extracts of Eucalyptus globulus Labillardiere, its allied species such as E.polybractea R.T.Baker or E.dives Schauer, Salvia officinalis L., its variety such as S.officinalis var.tenuior, Houttuynia cordata Thunb, Paeonia suffruticosa Andrews (P.moutan Sims), Paeonia lactiflora Pallas (P.albiflora Pail.), P.japonica Miyabe et Takeda, P. obovata Maxim. and P. veitchii Lynch. |