| 发明名称 |
Surface expression of enzyme in gene directed prodrug therapy |
| 摘要 |
<p>The invention provides a two component system for use in association with one another comprising: (a) a vector capable of expressing an enzyme at the surface of a cell; and (b) a prodrug which can be converted into an active drug by said enzyme, useful in the treatment of tumours.</p> |
| 申请公布号 |
EP0919622(A2) |
申请公布日期 |
1999.06.02 |
| 申请号 |
EP19980123229 |
申请日期 |
1995.07.27 |
| 申请人 |
CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED |
发明人 |
SPRINGER, CAROLINE JOY;MARAIS, RICHARD |
| 分类号 |
C12N15/09;A61K31/13;A61K31/35;A61K31/44;A61K35/76;A61K38/46;A61K38/48;A61K38/55;A61K45/00;A61K47/48;A61K48/00;A61P35/00;A61P43/00;C07K14/71;C12N5/10;C12N9/12;C12N9/48;C12N9/52;C12N15/57;C12R1/91;(IPC1-7):C12N15/57 |
主分类号 |
C12N15/09 |
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