发明名称 |
1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses |
摘要 |
Compounds of formula (I) and (II): [wherein R is hydrogen, halogen or alkyl; R1 is alkyl, amino or substituted amino; R2 is optionally substituted phenyl; R3 is hydrogen, halogen or optionally substituted alkyl; R4 is hydrogen, optionally substituted alkyl, cycloalkyl, aryl, or aralkyl] have valuable analgesic, anti-inflammatory, anti-pyretic and anti-allergic activities and have the ability to inhibit the production of leukotrienes and to inhibit bone resorption. They are relatively free from the side effects which generally result from the administration of compounds having these kinds of activities.
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申请公布号 |
US5908858(A) |
申请公布日期 |
1999.06.01 |
申请号 |
US19970824775 |
申请日期 |
1997.03.26 |
申请人 |
SANKYO COMPANY, LIMITED |
发明人 |
KIMURA, TOMIO;NOGUCHI, YASUO;NAKAO, AKIRA;SUZUKI, KEISUKE;USHIYAMA, SHIGERU;KAWARA, AKIHIRO;MIYAMOTO, MASAAKI |
分类号 |
A61K31/40;A61K31/402;A61P11/06;A61P19/10;A61P29/00;C07D207/32;C07D207/323;C07D207/325;C07D207/333;C07D207/36;(IPC1-7):A61K31/40;C07D207/335;C07D207/337 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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