发明名称 |
Process for producing L-glutamic acid by fermentation with E. coli resistant to aspartic acid antimetabolite |
摘要 |
A fermentative process for producing L-glutamic acid efficiently and at low cost is disclosed. Also disclosed are microorganisms having improved ability to produce L-glutamic acid. These microorganisms belong to the genus Escherichia, have resistance to an aspartic acid antimetabolite, and are deficient in alpha -ketoglutaric acid dehydrogenase activity. The process comprises cultivating one of these microorganisms in a liquid medium, accumulating L-glutamic acid in the culture medium, and collecting L-glutamic acid. In particular, E. coli AF13199 (FERM BP-5807).
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申请公布号 |
US5908768(A) |
申请公布日期 |
1999.06.01 |
申请号 |
US19970844857 |
申请日期 |
1997.04.23 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
ONO, EIJI;TSUJIMOTO, NOBUHARU;IZUI, HIROSHI;MATSUI, KAZUHIKO |
分类号 |
C12N15/09;C07H21/04;C12N1/21;C12P13/14;C12P13/16;C12R1/19;(IPC1-7):C12P13/14;C12N1/20 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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