发明名称 Pseudopolymorphic forms of 2-¬2-¬4-¬bis(4-fluorophenyl)methyl¾-1-piperazinyl¾ethoxy¾acetic acid dihydrochloride
摘要 The present invention relates to new pseudopolymorphic forms of 2-Ä2-Ä4-Äbis(4-fluorophenyl)methylÜ-1-piperazinylÜethoxyÜacetic acid dihydrochloride, namely, anhydrous 2-Ä2-Ä4-Äbis(4-fluorophenyl)methylÜ-1-piperazinylÜethoxyÜacetic acid dihydrochloride and 2-Ä2-Ä4-Äbis(4-fluorophenyl)methylÜ-1-piperazinylÜethoxyÜacetic acid dihydrochloride monohydrate. It also relates to processes for the preparation of these pseudopolymorphic forms and to pharmaceutical compositions containing them.
申请公布号 ZA9810780(B) 申请公布日期 1999.05.31
申请号 ZA19980010780 申请日期 1998.11.25
申请人 UCB. 发明人 MONIQUE BERWAER;GUY BODSON;MICHEL DELEERS;CHARLES DOGIMONT;DOMENICO FANARA;JAQUES TIMMERMANS
分类号 C07D295/08;A61K31/495;A61P11/08;A61P17/00;A61P25/08;A61P37/08;A61P43/00;C07D295/084;C07D295/088 主分类号 C07D295/08
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