发明名称 |
VACCINE AGAINST GRAM-NEGATIVE BACTERIAL INFECTIONS |
摘要 |
<p>A vaccine, effective in inducing the production of antibodies with which to immunize a second subject passively against infection by Gram-negative bacteria and LPS-mediated pathology, comprises a non-covalent polyvalent complex formed between purified, detoxified LPS derived from E. coli and purified outer membrane protein derived from N. meningitidis. The same vaccine will also actively immunize a host subject against Gram-negative bacterial infections and LPS-mediated pathology. Meningococcal infections are included among those Gram-negative bacterial infections protected against by the vaccine.</p> |
申请公布号 |
GR3029477(T3) |
申请公布日期 |
1999.05.28 |
申请号 |
GR19990400574T |
申请日期 |
1999.02.24 |
申请人 |
U.S. DEPARTMENT OF THE ARMY |
发明人 |
BHATTACHARJEE, APURBA;CROSS, ALAN;SADOFF, ERALD;ZOLLINGER, WENDELL |
分类号 |
A61K39/02;A61K39/095;A61K39/108;(IPC1-7):A61K39/095 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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