发明名称 NOVEL ISOXAZOLINE AND ISOXAZOLE DERIVATIVE FIBRINOGEN RECEPTOR ANTAGONISTS INTERMEDIATES, PREPARATION AND USE THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AS ACTIVE INGREDIENTS
摘要 This invention relates to novel isoxazolines and isoxazoles which are useful as antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex or the vitronectin receptor, to pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using these compounds, alone or in combination with other therapeutic agents, for the inhibition of platelet aggregation, as thrombolytics, and/or for the treatment of thromboembolic disorders.
申请公布号 HU9900102(A2) 申请公布日期 1999.05.28
申请号 HU19990000102 申请日期 1996.05.30
申请人 DUPONT PHARMACEUTICALS COMPANY 发明人 BATT,DOUGLAS GUY;CAIN,GARY AVONN;DEGRADO,WILLIAM FRANK;HUSSAIN,MUNIR ALWAN;MOUSA,SHAKER AHMED;OLSON,RICHARD ERIC;PINTO,DONALD;SIELECZKI-DZURDZ,THAIS MOTRIA;WITYAK,JOHN;XUE,CHU-BIAO
分类号 A61K31/42;A61K31/423;A61K31/425;A61K31/435;A61K31/44;A61K31/445;A61K31/47;A61K31/495;A61K31/496;A61K31/50;A61K31/505;A61K31/535;A61K31/5377;A61K31/55;A61K31/66;A61K31/665;A61K45/00;A61P1/00;A61P3/08;A61P3/10;A61P7/02;A61P7/04;A61P9/08;A61P9/10;A61P11/00;A61P17/00;A61P19/10;A61P27/02;A61P27/14;A61P29/00;A61P31/04;A61P35/00;A61P37/00;A61P37/08;A61P43/00;C07D261/04;C07D261/06;C07D261/10;C07D261/12;C07D261/18;C07D261/20;C07D413/04;C07D413/06;C07D413/12;C07D413/14;C07D417/12;C07D498/10;C07F7/10;C07F9/653;C07F9/6571 主分类号 A61K31/42
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