发明名称 |
NOVEL ISOXAZOLINE AND ISOXAZOLE DERIVATIVE FIBRINOGEN RECEPTOR ANTAGONISTS INTERMEDIATES, PREPARATION AND USE THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AS ACTIVE INGREDIENTS |
摘要 |
This invention relates to novel isoxazolines and isoxazoles which are useful as antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex or the vitronectin receptor, to pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using these compounds, alone or in combination with other therapeutic agents, for the inhibition of platelet aggregation, as thrombolytics, and/or for the treatment of thromboembolic disorders. |
申请公布号 |
HU9900102(A2) |
申请公布日期 |
1999.05.28 |
申请号 |
HU19990000102 |
申请日期 |
1996.05.30 |
申请人 |
DUPONT PHARMACEUTICALS COMPANY |
发明人 |
BATT,DOUGLAS GUY;CAIN,GARY AVONN;DEGRADO,WILLIAM FRANK;HUSSAIN,MUNIR ALWAN;MOUSA,SHAKER AHMED;OLSON,RICHARD ERIC;PINTO,DONALD;SIELECZKI-DZURDZ,THAIS MOTRIA;WITYAK,JOHN;XUE,CHU-BIAO |
分类号 |
A61K31/42;A61K31/423;A61K31/425;A61K31/435;A61K31/44;A61K31/445;A61K31/47;A61K31/495;A61K31/496;A61K31/50;A61K31/505;A61K31/535;A61K31/5377;A61K31/55;A61K31/66;A61K31/665;A61K45/00;A61P1/00;A61P3/08;A61P3/10;A61P7/02;A61P7/04;A61P9/08;A61P9/10;A61P11/00;A61P17/00;A61P19/10;A61P27/02;A61P27/14;A61P29/00;A61P31/04;A61P35/00;A61P37/00;A61P37/08;A61P43/00;C07D261/04;C07D261/06;C07D261/10;C07D261/12;C07D261/18;C07D261/20;C07D413/04;C07D413/06;C07D413/12;C07D413/14;C07D417/12;C07D498/10;C07F7/10;C07F9/653;C07F9/6571 |
主分类号 |
A61K31/42 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|