METHOD AND KIT FOR DETERMINING SEVERE INFLAMMATORY REACTIONS TO MOSQUITO BITES

摘要

Mosquito extract consisting essentially of antigens solely to allergens in mosquito saliva. Isolated and purified recombinant mosquito saliva antigens for use in skin tests, immunoassays and immunotherapy for allergic reactions to mosquito bites. A method for skin testing and determining the undertaking of immunotherapy includes the steps of administrating the isolated and purified mosquito salivary antigens to a patient and then recognizing skin reaction thereto is a positive indication of needing therapy. A kit and an immunoassay are also provided for measurement of mosquito salivary allergen specific IgE and IgG wherein the assay includes the isolated and purified recombinant mosquito allergens as a substrate to which allergen specific IgE and IgG binds. Antibodies directed against the recombinant salivary allergens of mosquitoes are also disclosed.