HIGH DRUG LOAD IMMEDIATE AND MODIFIED RELEASE ORAL DOSAGE FORMULATIONS AND PROCESSES FOR THEIR MANUFACTURE

摘要

This invention relates to high drug load granulation of (E)-.alpha.- 2-n-butyl-1- (4-carboxyphenyl) methyl!-1H- imidazol-5-yl! methylene-2-thiophenepropionic acid in the anhydrous form, a process for its production, compositions containing the compound and methods of using the compound to block angiotensin II receptors and to treat hypertension, congestive heart failure and renal failure.