| 摘要 |
A compound represented by general formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, and their medical applications. Since these compounds inhibit the action of chemokines such as MIP-1 alpha and/or MCP-1 on target cells, they may be useful as a therapeutic drug and/or preventative drug in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues. |
| 申请人 |
TEIJIN LIMITED;COMBICHEM, INC.;SHIOTA, TATSUKI;KATAOKA, KEN-ICHIRO;IMAI, MINORU;TSUTSUMI, TAKAHARU;SUDOH, MASAKI;SOGAWA, RYO;MORITA, TAKUYA;HADA, TAKAHIKO;MUROGA, YUMIKO;TAKENOUCHI, OSAMI;FURUYA, MONORU;ENDO, NORIAKI;TARBY, CHRISTINE, M.;MOREE, WILNA;TEIG, STEVEN, L. |
发明人 |
SHIOTA, TATSUKI;KATAOKA, KEN-ICHIRO;IMAI, MINORU;TSUTSUMI, TAKAHARU;SUDOH, MASAKI;SOGAWA, RYO;MORITA, TAKUYA;HADA, TAKAHIKO;MUROGA, YUMIKO;TAKENOUCHI, OSAMI;FURUYA, MONORU;ENDO, NORIAKI;TARBY, CHRISTINE, M.;MOREE, WILNA;TEIG, STEVEN, L. |
