发明名称 Cefalosporinas de vinil-pirrolidinona com substituintes básicos
摘要 <p>New discovery is associated with the cephalosporin derivatives of the general formula.(Formula 1) It is X CH or N; R1 is hydrogen or cyclopentyl; R2 is a group of formulas;(Formula group) R3 is an alkali-metal ion or third-degree ammonium group; R4 hydrogen is an amino preserver group, pyrrolidine-2-imethyl, azetidine-3-imethyl, iminomethyl, 1- carbamimidoyl; R5 is hydrogen, dialkylcarbamoyl, w-hydroxyalkyl, w-aminoalkyl, pyridinium-1-methyl, 1-hydroxy-3-aminomethyl- propyl or (hydroxyl)- pyrrolidine -2-il) methyl: R6 hydrogen, trifluoromethyl or hydroxyl; and R7 is alkyl, w-hydroxyalkyl, cycloalkyl, 3-pyrrolidinyl, 3-azetidinyl, iminomethyl or 1-carbamimidoyl.</p>
申请公布号 BR9705650(A) 申请公布日期 1999.05.25
申请号 BR19979705650 申请日期 1997.12.17
申请人 F. HOFFMANN-LA ROCHE AG. 发明人 PETER ANGEHRN;PAUL HEBEISEN;INGRID HEINZE-KRAUSS;MALCOLM PAGE;VALERI RUNTZ
分类号 A61K;A61K31/00;A61K31/545;A61K38/00;C07D;C07D213/00;C07D417/12;C07D501/06;C07D501/18;C07D501/24;C07D501/34;C07D501/46;C08F;C12P41/00;(IPC1-7):C07D501/46 主分类号 A61K
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