| 摘要 |
A method and compounds are provided for inhitibing the expression of insulin-like growth factor-1 receptor in tumor cells. An important aspect of the invention is the discovery that the antisense compounds of the invention are strong inducers of prefential apoptosis in tumor cells. Antisense compounds of the invention are directed to codons 4 through 9 of the messenger RNA encoding human insulin-like growth factor-1 receptor. |
