DERIVATIVES OF 1,2,4-TRIAZOLO[1,5-B]PYRIDAZINE OR THEIR SALTS, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF PATIENT TREATMENT

摘要

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of 1,2,4-triazolo- -[1,5-b]pyridazine of the general formula (I) where R1, R2, R - H or lower alkyl; X - oxygen atom or sulfur; Y - a group -CR4R ; R4, R - H, lower alkyl or a group of the formula (a); R6, R - H or lower alkyl or with an adjacent nitrogen atom they form piperazino-group possibly substituted with lower alkyl-group; m, n - a whole number 0-4, or their salts showing anti-allergic, anti-inflammatory and anti-öÇÆ activity. EFFECT: improved method of synthesis, curative activity. 19 cl, 4 tbl, 56 ex