| 摘要 |
<p>A process for the crystallization of β-lactam compounds involving simultaneous addition of a solution of said β-lactam compound and a titrant to a crystallization vessel. In case of zwitterionic β-lactam compounds, the pH-value is maintained between 2.5 and 7.5, preferably between the isoelectric point of said compound and 7.5 and at a temperature between 0 °C et 50 °C.</p> |
