ANTIMICROBIAL CEMENT COMPOSITIONS

摘要

Antimicrobial cement compositions are disclosed which contain antimicrobial zeolites. Preferred are antimicrobial cement compositions having dental applications including fillers, adhesives, sealants and restorative materials, and medical applications such as bone cements, implant components and bone substitutes. A particularly preferred cement is an antimicrobial glass ionomer cement composition for dental use comprising a polyelectrolyte, glass ionomer particles, and antimicrobial zeolite particles. When the composition is cured to form a hardened cement, the glass ionomer particles and the zeolite particles form ionic bonds with the polyelectrolyte, the zeolite particles being present in the composition in an amount sufficient to prevent growth of bacteria in the composition and over the hardened cement formed by curing the composition. Preferably, the zeolite contains an antimicrobial metal ion such as silver ion, and is present in the glass ionomer cement composition in an amount of from about 0.2 % to about 20 % by weight of the glass ionomer particles.