发明名称 FORMULATION OF A COMBINATION COMPRISED OF OPIOID AND α - ADRENERGIC AGONISTS AND THE APPLICATION THEREOF
摘要 <p>The invention relates to a formulation containing an opioid combined with an α-adrenergic agonist or pharmaceutically applicable salt of the active substances and additional auxiliary agents, wherein the dosing unit is used in a quantity between 1 νg and 500 νg for the α-adrenergic agonist, and the dosing unit is used in a quantity between 0.5 and 50 mg for the opioid such that no centrally conditioned cardiovascular effect occurs. The invention also relates to the application of the formulation as analgesics.</p>
申请公布号 WO1999024023(A2) 申请公布日期 1999.05.20
申请号 EP1998006923 申请日期 1998.11.02
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