发明名称 |
PROCESS FOR PREPARATING OPTICALLY ACTIVE COMPOUNDS |
摘要 |
<p>The present invention relates to a novel, highly practical method for producing optically active compounds such as optically active alcohol and optically active amine useful for various utilities such as synthetic intermediates of drugs, liquid crystal materials, and optical resolution agents, comprising hydrogen transfer-type asymmetric reduction in the presence of a transition metal catalyst and an optically active nitrogen-containing compound or a transition metal catalyst with an optically active nitrogen-containing compound as the asymmetric ligand, and a hydrogen-donating organic or inorganic compound. In accordance with the present invention, characteristically, an optically active secondary alcohol can be recovered through the hydrogen transfer-type oxidation from racemic secondary alcohol or meso-type diol.</p> |
申请公布号 |
EP0916637(A1) |
申请公布日期 |
1999.05.19 |
申请号 |
EP19960941186 |
申请日期 |
1996.12.06 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY CORPORATION;NKK CORPORATION;TAKEDA CHEMICAL INDUSTRIES, LTD.;ASAHI KASEI KOGYO KABUSHIKI KAISHA;TAKASAGO INTERNATIONAL CORPORATION |
发明人 |
IKARIYA, TAKAO;HASHIGUCHI, SHOHEI;TAKEHARA, JUN;UEMATSU, NOBUYUKI;MATSUMURA, KAZUHIKO;NOYORI, RYOJI;FUJII, AKIO |
分类号 |
B01J31/02;B01J31/18;B01J31/22;C07C29/143;C07C67/31;C07C209/52;C07C211/27;C07C211/30;C07C211/40;C07C213/02;C07C217/84;(IPC1-7):C07C31/02;C07C211/41;C07C211/52;C07C239/08;C07C239/20;C07B31/00;C07B53/00;C07M7/00;C07C29/17 |
主分类号 |
B01J31/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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