发明名称 |
INDUCED PROLIFERATION OF ANTIGEN-SPECIFIC IMMUNOSUPPRESSIVE CELL AND CULTURE TOOL USED THEREFOR |
摘要 |
PROBLEM TO BE SOLVED: To prepare a large amount of an antigen-specific immunosuppressive cell holding an intact strong antigen-specific immunosuppressive ability by culturing a human cell in the presence of an antigen and further culturing the resultant cultured human cell in a culture tool containing an immobilized protein. SOLUTION: A human cell is cultured in the presence of one or more antigens and the resultant cultured human cell is further cultured in a culture tool containing an immobilized protein which is an antibody or the like against the surface antigen of the human cell. The obtained cell is useful for treating diseases associated with anomalous acceleration of the immunological system such as treatment of autoimmune diseases or suppression of rejection of organ transplantation with slight adverse effects. |
申请公布号 |
JPH11127851(A) |
申请公布日期 |
1999.05.18 |
申请号 |
JP19970301966 |
申请日期 |
1997.11.04 |
申请人 |
KANEGAFUCHI CHEM IND CO LTD |
发明人 |
YAMASHITA KENJI;FUKUCHI TAKESHI |
分类号 |
G01N33/531;A61K35/14;A61K38/00;A61K38/28;A61K39/00;A61P3/08;A61P3/10;A61P29/00;A61P37/06;C07K16/24;C07K16/28;C12M3/00;C12N5/07;C12N5/078;G01N33/564 |
主分类号 |
G01N33/531 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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