| 摘要 |
An erythromycin A derivative represented by the formula:wherein n is an integer of from 1 to 8, R1 is a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, R2 is a pyridylmethyl group, a quinolylmethyl group, a pyridylsulfonyl group or quinolylsulfonyl group, R3 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or a cinnamyl group, R4 is a cladinosyloxy group or a group represented by the formula:wherein m is 0 or 1, R5 is a pyridyl group, a quinolyl group, a phenyl group, a phenyl group substituted with one, two or three members selected from alkyl groups having 1 to 6 carbon atoms, a nitro group, alkoxy groups having 1 to 3 carbon atoms and halogen atoms, or a pyridyl or quinolyl group substituted with one or two members selected from alkyl groups having 1 to 6 carbon atoms, a nitro group, alkoxy groups having 1 to 3 carbon atoms and halogen atoms; or a pharmaceutically acceptable salt thereof. |
