CONTROL OF LYMPHOCYTE LOCALIZATION BY LEEP-CAM ACTIVITY
摘要
A novel cell surface glycoprotein, LEEP-CAM, is disclosed. This invention further provides methods for treating inflammatory disorders in mammals through the administration of compositions which are modulators of LEEP-CAM activity. Antibodies are also disclosed which prevent LEEP-CAM-mediated migration of lymphocytes into epithelial layers of cells.
申请公布号
WO9922765(A1)
申请公布日期
1999.05.14
申请号
WO1998US23158
申请日期
1998.10.30
申请人
BRIGHAM AND WOMEN'S HOSPITAL;BRENNER, MICHAEL, B.;PARKER, CHRISTINA, M.;SCHOEN, MICHAEL, P.
发明人
BRENNER, MICHAEL, B.;PARKER, CHRISTINA, M.;SCHOEN, MICHAEL, P.
