发明名称 PROCESS FOR THE PREPARATION OF HYDROXY SUBSTITUTED GAMMA BUTYROLACTONES
摘要 Preparation of 4-hydroxy substituted butyrolactones is described. A process for the preparation of 3-hydroxybutyrolactone, 1,2,4-trihydroxybutane and 3,4-dihydroxy acid methyl ester from malic acid is particularly described. The preparation of 4-hydroxymethyl-4-hydroxybutyric acid-1-methyl ester and 4-hydroxymethyl butyrolactone is particularly described. The compounds are intermediates to various pharmaceutical and agricultural products.
申请公布号 WO9923086(A1) 申请公布日期 1999.05.14
申请号 WO1998US20448 申请日期 1998.09.29
申请人 MICHIGAN STATE UNIVERSITY 发明人 HOLLINGSWORTH, RAWLE, I.
分类号 C07D307/33;C07C27/04;C07C29/147;C07C31/22;C07C67/31;C07C69/675;C07D315/00;(IPC1-7):C07D307/32;C07C27/06;C07C27/08 主分类号 C07D307/33
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