摘要 |
<p>Optically active materials of tricyclic compounds, for example, cyclopentaÄbÜ benzofuran derivatives represented by the following formula: <CHEM> Äwherein R1, R2, Y and Z independently represent hydrogen, halogen, an alkyl group, or an aryl group; W represents oxygen, sulfur, nitrogen or carbon; and n represents 0 to 4Ü are directly produced by adding an optically active alcohol, amine and/or metal salt thereof. The production method of the present invention requires neither complicated optical resolution operation nor enzyme reaction requiring a large amount of solvent and much reaction time and exhibiting low reproducibility, can be applied to both experimental and industrial production methods, and is thus very advantageous.</p> |