Spray dried vaccine preparation comprising aluminium adsorbed immunogens

摘要

PCT No. PCT/AU93/00677 Sec. 371 Date Jul. 10, 1995 Sec. 102(e) Date Jul. 10, 1995 PCT Filed Dec. 24, 1993 PCT Pub. No. WO94/15636 PCT Pub. Date Jul. 21, 1994Vaccine preparations in stable particulate form are disclosed. An immediate-release preparation comprises an immunogen adsorbed to an aluminum adjuvant. A controlled- or delayed-release preparation comprises microspherical particles comprising a continuous matrix of biodegradable polymer containing discrete, immunogen-containing regions.