发明名称 |
SUSTAINED-RELEASE FORMULATION OF ANIMAL GROWTH HORMONE AND PROCESS FOR PREPARATION THEREOF |
摘要 |
The present invention relates to a sustained-release formulation of an animal growth hormone and a process for preparation thereof, comprising a step to produce solid pellets by mixing an animal growth hormone and an excipient in accordance with a direct tabletting method and a step to coat the pellets with a film comprising a biodegradable polymer and a poloxamer. The thus obtained formulation has small initial drug release, and shows a continuous and uniform effect when administered. Further, the formulation of the present invention may be produced economically in a large scale.
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申请公布号 |
CA2194610(C) |
申请公布日期 |
1999.05.11 |
申请号 |
CA19972194610 |
申请日期 |
1997.01.08 |
申请人 |
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发明人 |
KIM, AE-RI;KIM, NAM-JOONG;JUNG, MIN-HEE |
分类号 |
A61K9/52;A61K9/00;A61K9/22;A61K9/50;A61K38/27;(IPC1-7):A61K38/27;A61K9/32 |
主分类号 |
A61K9/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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