发明名称 Method for treating the epithelium of bodily orifices with chlorine dioxide and a phosphate compound
摘要 A stable solution, cream, salve, or spray composition containing chlorine dioxide and a phosphate, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium monofluorophosphate, is disclosed for the prevention and treatment of abnormal conditions of the epithelium of bodily orifices. Examples of such abnormal conditions of the epithelium of the rectal, vaginal, urethral, oral, nasal, ocular, and auditory canal orifices brought about by any of leukoplakia, hairy leukoplakia, vaginitis, endometriosis, Candida Albicans, Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Pseudomonades, Candida species, and leukoplakia vulvae. The preferred concentration ranges are between about 0.005%-2.0% chlorine dioxide, and between about 0.02%-3.0% phosphate. The phosphate compound retards escape of chlorine dioxide in the pH range of 6.0 to 7.4, at which pH chlorine dioxide becomes activated and releases sufficient chlorine dioxide to reduce motility and become lethal to the involved micro-organisms.
申请公布号 US5902575(A) 申请公布日期 1999.05.11
申请号 US19980066705 申请日期 1998.04.27
申请人 MICROPURE, INC. 发明人 RATCLIFF, PERRY A.
分类号 A61K8/20;A61K8/22;A61K8/24;A61K9/00;A61K33/40;A61K33/42;A61K47/02;A61Q11/00;A61Q15/00;A61Q19/00;(IPC1-7):A61K9/10 主分类号 A61K8/20
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