发明名称 |
SOLID STATE SOLUTIONS AND DISPERSIONS OF POORLY WATER SOLUBLE DRUGS |
摘要 |
The invention provides a composition useful as a pharmaceutical excipient, the method of producing same, and the pharmaceutical compositions obtained thereby. In particular, the invention has applicability to increasing the solubility of poorly soluble therapeutically active compounds, by means of an excipient comprising a mixture of: (a) saturated polyglycolyzed glycerides, and (b) polyoxypropylene-polyoxyethylene block copolymers, whereby the solubility of the poorly soluble therapeutically active compound in the pharmaceutical composition is enhanced.
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申请公布号 |
WO9921534(A1) |
申请公布日期 |
1999.05.06 |
申请号 |
WO1998EP06544 |
申请日期 |
1998.10.15 |
申请人 |
MERCK PATENT GMBH |
发明人 |
TALLAVAJHALA, SIVA, NARAYAN;LIU, XIUYING |
分类号 |
A61K47/34;A61K9/14;A61K9/20;A61K9/48;A61K31/192;A61K31/4166;A61K31/4422;A61K45/00;(IPC1-7):A61K9/14 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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