摘要 |
<p>The present invention relates to the use of macrophages in the function of antigen presenting cells (APC) to redirect the balance of the CD4+ T helper 1 (Th1)/CD4+ T helper 2(Th2) cell subsets during an immune response. More particularly, the present invention is directed to pharmaceutical formulations comprising macrophages or a cell population containing macrophages, optionally together with a suitable excipient, and methods for suppressing the Th2 dependent humoral immune response and/or to stimulate the Th1 dependent, cellular immune response.</p> |