发明名称 INDUCIBLE CELLULAR IMMUNITY THROUGH ACTIVATION OF Th1 AND SUPPRESSION OF Th2 RESPONSES BY MACROPHAGES
摘要 <p>The present invention relates to the use of macrophages in the function of antigen presenting cells (APC) to redirect the balance of the CD4+ T helper 1 (Th1)/CD4+ T helper 2(Th2) cell subsets during an immune response. More particularly, the present invention is directed to pharmaceutical formulations comprising macrophages or a cell population containing macrophages, optionally together with a suitable excipient, and methods for suppressing the Th2 dependent humoral immune response and/or to stimulate the Th1 dependent, cellular immune response.</p>
申请公布号 WO1999021968(A1) 申请公布日期 1999.05.06
申请号 EP1998006986 申请日期 1998.10.22
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