SENSOREN FÜR NEUTRALE MOLEKÜLE

摘要

PCT No. PCT/GB94/02276 Sec. 371 Date Apr. 23, 1996 Sec. 102(e) Date Apr. 23, 1996 PCT Filed Oct. 18, 1994 PCT Pub. No. WO95/11449 PCT Pub. Date Apr. 27, 1995A method for the detection of chemical agent present in a material comprising exposing a calixarene, having redox active substituents on its para rim, to a solution or suspension derived by admixture of all or some of the material with a liquid measuring any change in electrical behavior of the calixarene during or after exposure to the solution or suspension as compared to a reference condition, and relating such change in electrical behavior to the presence of chemical agent. Preferably, the calixarene exposed to the solution or suspension is a calix[4]arene or general formula (J), wherein Y1 to Y4 are independently selected from hydrogen, alkyl, alkenyl, aryl, aralkyl or a redox active substituent and R1 to R4 are independently selected from hydrogen, alkyl, alkenyl, aryl, aralkyl, or a polymerisable moiety, wherein at least one of Y1 to Y4 is a redox active substituent.