ASSAY FOR IN VITRO MEASUREMENT OF AMINO-TELOPEPTIDES OF TYPE1 COLLAGEN

摘要

Methods of determining type I collagen degradation in vivo are provided by deter mining the presence or concentration of a peptide in a body fluid, the peptide being an N-terminal type I collagen telopeptide fragment containing a hydroxylysyl pyridinoline or lysyl pyridinoline cross-link . Kits comprising an immunological binding partner which binds to a type I collagen telopeptide fragm entused to assay these peptides in a body fluid are also described.