发明名称 |
N-heteroarenesulfonyl-protected amino acid reagents for peptide synthesis |
摘要 |
This invention relates to the use of heteroarenesulfonyl groups as protecting groups for amino groups, particularly the amino groups of amino acids, and specifically to nitrogen-protected (N-protected) amino acid reagents, which are particularly well-suited for use in peptide syntheses. In particular, the N-protected amino acid reagent is an N-heteroarenesulfonyl-protected amino acid halide. The heteroarenesulfonyl protecting groups are readily removed under relatively mild conditions.
|
申请公布号 |
US5900427(A) |
申请公布日期 |
1999.05.04 |
申请号 |
US19960646747 |
申请日期 |
1996.05.03 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
VEDEJS, EDWIN;WANG, JIABING;LIN, SHOUZHONG;KLAPARS, ARTIS |
分类号 |
C07D277/76;C07D277/80;C07D285/12;C07D285/125;C07D417/12;C07K1/06;C07K5/065;(IPC1-7):A61K31/425 |
主分类号 |
C07D277/76 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|