发明名称 |
Bead linkers for immobilizing nucleic acids to solid supports |
摘要 |
Novel compositions comprised of at least one bead conjugated to a solid support and further conjugated to at least one nucleic acid and preferred methods for making the novel compositions are described. As compared to "flat" surfaces, beads linked to a solid support provide an increased surface area for immobilization of nucleic acids. Furthermore, by selecting a bead with the desired functionality, a practitioner can select a functionalization chemistry for immobilizing nucleic acids, which is different from the chemistry of the solid support.
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申请公布号 |
US5900481(A) |
申请公布日期 |
1999.05.04 |
申请号 |
US19960746036 |
申请日期 |
1996.11.06 |
申请人 |
SEQUENOM, INC. |
发明人 |
LOUGH, DAVID M.;KOESTER, HUBERT |
分类号 |
C07F9/24;C07H21/00;C12Q1/68;C40B40/06;C40B40/10;C40B60/14;G01N35/10;(IPC1-7):C07H1/00;C07H21/04;C07H33/18 |
主分类号 |
C07F9/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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