| 发明名称 |
USE OF AN INHIBITOR OF THE DEPHOSPHORYLATION OF DARPP-32 FOR TREATING SCHIZOPHRENIA |
| 摘要 |
The present invention discloses the bidirectional regulation of DARPP-32 phosphorylation by dopamine and dopamine D1 and D2 receptors. This disclosure leads to new methodology in the treatment of schizophrenia and related disorders. In addition, the present invention provides methods for identifying agents that can be used in such treatment.
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| 申请公布号 |
WO9920273(A1) |
申请公布日期 |
1999.04.29 |
| 申请号 |
WO1998US22127 |
申请日期 |
1998.10.19 |
| 申请人 |
THE ROCKEFELLER UNIVERSITY |
发明人 |
NISHI, AKINORI;SNYDER, GRETCHEN, L.;FIENBERG, ALLEN, A.;GREENGARD, PAUL |
| 分类号 |
A61K31/00;A61K31/436;G01N33/68;(IPC1-7):A61K31/435 |
主分类号 |
A61K31/00 |
| 代理机构 |
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