发明名称 |
CELL LINES USEFUL FOR IN VITRO ASSAY FOR IDENTIFICATION OF CARCINOGENS |
摘要 |
Disclosed are test cells useful for evaluating the carcinogenicity of a compound using a transformation assay. The test cell preferably is transfected with an oncogenic viral recombinant nucleic acid molecule encoding a transforming protein. Cell growth is scored to identify the presence or absence of a transformation characteristic, such as formation of foci, loss of growth factor or serum requirements or anchorage independence. The development of such a transformation characteristic indicates that the compound being tested is carcinogenic.
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申请公布号 |
CA2306693(A1) |
申请公布日期 |
1999.04.29 |
申请号 |
CA19982306693 |
申请日期 |
1998.10.14 |
申请人 |
VIRATEST CARCINOGEN MONITORING, LTD. |
发明人 |
KOWALSKI, LINDA A. |
分类号 |
C12N15/09;C07K14/025;C12N5/08;C12N15/85;C12Q1/02;G01N33/15;G01N33/50;G01N33/574;(IPC1-7):C12N5/10 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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