摘要 |
<p>The invention provides S-(+)-3-{ 1-(1,3-benzodioxol -5-yl)-2-[ (2-methoxy-4- methylphenyl)sulfonylamino] -2-oxoethyl }-1-methyl -1H-indole- 6-carboxylic acid, represented by formula (a), which is substantially free from its (R)-(-)-enantiomer, and pharmaceutically acceptable derivatives thereof. The compound is useful in the treatment of inter alia acute renal failure, restenosis and pulmonary hypertension.</p> |